Obstetric Medicine > Volume 2, Number 1 > Pp. 21-25

This Article Figures Only Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Lim, E L Articles by Taylor, R Search for Related Content Social Bookmarking                      What's this?

Original articles

Intrauterine growth rate in pregnancies complicated by type 1, type 2 and gestational diabetes

E L Lim MRCP   ^*, T Burden MBChB   ^*, S M Marshall MD   ^*, J M Davison MD   , M J Blott MRCOG   , J S J Waugh MRCOG    and R Taylor MD   ^* 

^* The Directorates of Medicine; Directorates of Women's Services, Royal Victoria Infirmary, Newcastle upon Tyne, UK

Correspondence to: Professor Roy Taylor Email: roy.taylor{at}ncl.ac.uk

Fetal macrosomia is a feature of all subtypes of maternal diabetes. The intrauterine time course of development of macrosomia in type 1, type 2 and gestational diabetes (GDM) could identify the times of more rapid growth, which differ as a result of different influences in subtypes of diabetes. Higher maternal weight in type 2 and GDM may be expected to contribute to macrosomia and the blood glucose control will exert an additional influence. Information was collected prospectively on 217 pregnancies in insulin-treated women at a single centre over a six-year period. All women were managed by a single team of obstetricians and diabetologists at a Joint Obstetric Medical Clinic. The rate of increase in abdominal circumference from 28 weeks was identical in each subtype of diabetes and there were no differences between subtypes at the earliest gestation assessed. Use of customized growth centiles showed rates of macrosomia to be similar in type 1, type 2 and GDM (43.0%, 50.0% and 41.8%, respectively). The intrauterine time course to macrosomia is similar in type 1, type 2 and GDM. The relationship of macrosomia to extent of elevation of mean blood glucose control is weak, implying a low threshold for maximal effect on the rate of fetal growth.

Key Words: intrauterine growth • diabetes • macrosomia • customized growth centile

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				M. Peek and R. Nanan Intrauterine growth rates in diabetic pregnancies and clinical outcomes Obstet Med, September 1, 2009; 2(3): 132 - 132. [Full Text] [PDF]